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Strong recall of cellular processes and components
Good ability to evaluate biological arguments
Strong understanding of cause-effect relationships
Adequate ability to assess information validity
Needs improvement in applying concepts to new scenarios
Good understanding of broader scientific context
Cellular respiration is how cells break down glucose to produce energy in the form of ATP. The process has three main stages: glycolysis, the Krebs cycle, and the electron transport chain.
First, glycolysis happens in the cytoplasm of the cell. In this stage, one glucose molecule (6 carbon atoms) is split into two molecules of pyruvate (3 carbon atoms each). This produces a small amount of ATP and NADH. Glycolysis doesn't require oxygen, so it can occur in both aerobic and anaerobic conditions.
Next, if oxygen is present, the pyruvate enters the mitochondria and goes through the Krebs cycle (also called the citric acid cycle). First, pyruvate is converted to acetyl-CoA, releasing CO2. Then the acetyl-CoA goes through a series of reactions that generate NADH, FADH2, and a little ATP. More CO2 is released during this process, but the specific enzymes involved in each step are not clearly identified.
Finally, the NADH and FADH2 from earlier stages enter the electron transport chain, which is in the inner membrane of the mitochondria. Here, electrons are passed along a series of proteins, which pumps H+ ions across the membrane to create a gradient. This gradient drives ATP synthase to produce most of the ATP. At the end of the chain, oxygen accepts the electrons and combines with H+ to form water. The total ATP yield is about 36 ATP molecules.
This response demonstrates a good understanding of cellular respiration, covering all three main stages correctly. The student shows strong knowledge of glycolysis and basic understanding of the Krebs cycle.
Electron transport chain details and chemiosmosis
Chapter 9.3, Interactive ATP Synthesis Simulation
Focus on deepening your understanding of the electron transport chain, particularly the mechanism of chemiosmosis and how ATP synthase uses the proton gradient.
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